Open slow cooker liner and place it inside slow cooker bowl. Fit liner snugly against the bottom and sides of bowl; pull top of liner over rim of bowl.

Pour the vegetable juice and water into the lined-slow cooker. Add beef, vegetables, ketchup, bouillon and pepper; stir gently. Place lid on slow cooker.

Cook on low for 8 to 9 hours or on high 4 to 5 hours until beef is tender.

Carefully remove lid to allow steam to escape. Serve food directly from lined-slow cooker. Do not lift or transport liner with food inside. Cool slow cooker completely; remove liner and toss.