Make chicken: In a large, deep-sided skillet over medium heat, cook bacon until crispy and fat is rendered, 4 to 5 minutes. Using a slotted spoon, transfer bacon to a plate; keep bacon fat in skillet.

In a shallow dish, whisk together flour, salt, pepper, Italian seasoning, onion powder, and garlic powder. Return skillet to medium-high heat. Lightly coat chicken cutlets in flour mixture and add to skillet. Cook, flipping halfway, until both sides are deeply golden, 4 to 6 minutes per side. Transfer chicken to a plate.

Make panko topping: Return skillet to medium-low heat. Add oil, panko bread crumbs, Italian seasoning, everything bagel seasoning, salt, pepper, and red pepper flakes. Cook, stirring frequently, until panko mixture is golden, 5 to 6 minutes. Transfer to a bowl.

Make sauce: Return skillet to medium heat and add oil, garlic, pepper, and red pepper flakes (if using). Cook, stirring, until garlic is golden. Add marinara, sugar, and water and bring to a simmer.

Add pasta and cook, stirring occasionally, until noodles are al dente and sauce is creamy, about 12 minutes.

Fold in half the mozzarella and Parmesan until melty. Slice cooked chicken on the bias into strips and place on top of pasta. Remove skillet from heat, sprinkle with remaining mozzarella and Parmesan, and cover with lid to melt cheese, about 4 minutes.

Garnish with panko topping, cooked bacon, and fresh herbs.